23 12月 2022 gabriels



  • 王强斌,中国科学院苏州纳米技术与纳米仿生研究所
  • 裴仁军,中国科学院苏州纳米技术与纳米仿生研究所


The CAS Key Laboratory of Nano-Bio Interface was founded in 2014 at Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences (CAS). With a multi-disciplinary research team, the Laboratory focuses on the major scientific challenges to the nano-bio interfaces between nanomaterials and biosystems, aiming to interpret and optimize the interactions between them for advancing the applications of nanotechnology in life science. In past years, three main directions were developed:

  1. Nano-bio interface design and regulation: this is to achieve the specific recognition between nanomaterials and biological entities for biosensing, diagnosis, selective targeting, etc., with the help of multiple techniques such as aptamer and peptide screening, nanomaterials synthesis and modifications, self-assembly.
  2. In vivo nano-imaging: employing near-infrared II (NIR-II) fluorescence imaging and magnetic resonance imaging (MRI) for in vivo imaging with high sensitivity and high temporal-spatial resolution. The research covers the preparation and functionalization of nanoprobes, the development of imaging instruments and imaging-based biomedical applications.
  3. Nanotechnology and stem cells: the research focuses on developing three-dimensional functionalized biomaterial scaffolds by integration of nanomaterials to mimic tissue properties and construct favorable microenvironments for modulating cell fate and promoting tissue regeneration.

This Focus Collection will include a series of topical reviews and original research articles that highlight the recent advances in nanomaterials-based detection and in vivo imaging, biomaterial scaffold and cell-based therapy from the researchers of CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences.


Topical Review

Recent advances of engineered and artificial drug delivery system towards solid tumor based on immune cells

Zhuqing Sun et al 2022 Biomed. Mater. 17 022002



A functional extracellular matrix biomaterial enriched with VEGFA and bFGF as vehicle of human umbilical cord mesenchymal stem cells in skin wound healing

Zhongjuan Xu et al 2022 Biomed. Mater. 17 014103


Advanced NIR ratiometric probes for intravital biomedical imaging

Haoying Huang et al 2022 Biomed. Mater.17 014107


Aptamer-functionalized targeted siRNA delivery system for tumor immunotherapy

Haiyin Lv et al 2022 Biomed. Mater. 17 024108


Biomaterials with stiffness gradient for interface tissue engineering

Jialun Cai et al 2022 Biomed. Mater. 17 064103


Cell-derived extracellular matrix enhanced by collagen-binding domain-decorated exosomes to promote neural stem cells neurogenesis

Yuanxin Zhai et al 2022 Biomed. Mater. 17 014104


Clinical application of collagen membrane with umbilical cord-derived mesenchymal stem cells to repair nasal septal perforation

Handong Wang et al 2022 Biomed. Mater. 17 014101


Flexible conductive silk-PPy hydrogel toward wearable electronic strain sensors

Yuanyuan Han et al 2022 Biomed. Mater. 17 024107


Improved oral delivery of insulin by PLGA nanoparticles coated with 5β-cholanic acid conjugated glycol chitosan

Weizhi Wang et al 2021 Biomed. Mater. 16 064103


Linear-branched poly(β-amino esters)/DNA nano-polyplexes for effective gene transfection and neural stem cell differentiation

Yuheng Cao et al 2022 Biomed. Mater. 17 024105


Multifaceted tannin crosslinked bioinspired dECM decorated nanofibers modulating cell–scaffold biointerface for tympanic membrane perforation bioengineering

Zahid Hussain et al 2022 Biomed. Mater. 17 034102


Optimized, visible light-induced crosslinkable hybrid gelatin/hyaluronic acid scaffold promotes complete spinal cord injury repair

Xinhao Zhao et al 2022 Biomed. Mater. 17 024104


Smart delivery of poly-peptide composite for effective cancer therapy

Xin Yuan et al 2022 Biomed. Mater. 17 024103


Long-term stability, high strength, and 3D printable alginate hydrogel for cartilage tissue engineering application

Yun Chu et al 2021 Biomed. Mater. 16 064102


Biomedical Materials

  • 2021年影响因子:4.103  Citescore:5.5
  • Biomedical Materials(BMM)期刊是IOP出版社旗下基于同行评议的学术期刊,创刊于2006年。该刊关注如何利用生物医学材料解决日益增长的人类健康需求,包括但不限于组织工程以及、再生医学、干细胞、药物/因子递送、纳米医学、癌症诊断和治疗等领域的应用基础研究和临床转化研究。